Test Booster Res100

[Darkoz]

Fastest Googler in the west

 

[O.N.]

ON what do you make of this Resveratrol Inhibits mTOR Signaling by Promoting the Interaction between mTOR and DEPTOR seems to inhibit growth?

They are discussing the effects resveratrol has on anti aging etc and how resveratrols protective effects (on various cardiovascular and metabolic disorders) may occur through inhibition of the mammalian target of rapamycin (mTOR) signaling pathway.

You have to remember these are test tube studies and in the world of science for every study with 1 opinion there is usually 5 others with the opposite opinion.....especially when it comes to test tube studies.

This is why studies advance from:

• test tubes
• to rats
• then on to dogs, monkeys
• and then finally in humans.

Below are several studies which show in living subjects not test tubes the benefit resveratrol has on muscle.

1. Researchers from University of Alberta explored what effects resveratrol might have on exercise performance in rats. The study was just recently published in Journal of Physiology. In the study they subjected rats to training on a treadmill five days a week for 12 weeks. They used air puffs and electric shock to prod the rats to run and the training was made progressively more difficult over time. The rats ran essentially to exhaustion (where they couldn’t be prodded anymore).

These exercising rats were divided into two groups. The first group received resveratrol in their chow (4g per Kg chow) and the second group just ate a control chow. The resveratrol group experienced a striking 21% increase in exercise performance versus the control group. The force generation in the slow twitch soleus muscle was also enhanced significantly over control. Fatty acid metabolism by muscle was enhanced in the resveratrol group versus control as well. Finally, the efficiency and structural integrity of the heart muscle was improved more so in the resveratrol group.

So it appears that resveratrol can be an effective enhancer of performance and it appears to do this in large part by supporting the efficient utilization of fatty acids for fuel.

2. Improvements in skeletal muscle strength and cardiac function induced by resveratrol during exercise training contribute to enhanced exercise performance in rats. Improvements in skeletal muscle strength and cardi... [J Physiol. 2012] - PubMed - NCBI

So as you can see in the above study moving beyond a test tube and into something that is living it actually increases muscle strength and function and that's not even going into detail about the effects resveratrol has on muscle mitochondria cells.


Mitochondria:
1. Here is another study discussing the effects resveratrol has on protecting mitochondria http://www.medscape.com/viewarticle/745451


2. Here is another discussing the effects resveratrol has on muscle mitochondria showing that it helps in maintaining basal mitochondrial content and a larger role in preserving mitochondrial function.
Sirtuin 1-mediated Effects of Exercise and Resveratrol on Mitochondrial Biogenesis

3. Direct quote from the study by Lagouge et al, (2006), Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1.

A striking feature of the myofiber is its ability to transform and remodel in response to environmental demands. The most notable is exercise training, which transforms the metabolic status of the myofiber to one of increased oxidative metabolism and switches the fiber from one of a fast twitch type 2 to a slow twitch type 1 (Booth et al., 2002). In this study, RSV treatment of HF-fed mice induced a similar myofiber remodeling but in the absence of increased physical activity. The myofibers from RSV-treated mice were enriched in mitochondria, exhibited enhanced oxidative capacity, and displayed a higher resistance to fatigue because of the concerted activation of a genetic program geared for aerobic metabolism. Although we were unable to prove that these progressive changes in oxidative capacity by RSV lasted long enough to induce a complete type 1 fiber transformation, we did see advanced improvement in motor function, which is a component of the integrated physiological response required to improve exercise performance. Comparable changes in muscle fiber types have been recapitulated in genetically engineered mouse models that trigger calcium regulatory pathways (Wu et al., 2002), mimic PPARβ/δ activation (Wang et al., 2004), or enhance PGC-1a activity (Lin et al., 2002a). The fact that RSV induces a muscle fiber type switch in the absence of genetic engineering underscores its powerful pharmacological activities. RSV could hence be viewed as a performance-enhancing drug, which, in contrast to other pharmacological mediators, such as anabolic steroids, improves performance by changing myofiber specificity rather than by increasing muscle mass.


(In this instance below Res preserves IGF1 vs caloric restriction)

4. "Following two months of dietary intervention, we observed reduced IGF-1 levels in CR mice, but not in resveratrol treated mice (Figure 2B). We did not observe significant alterations in any other hormones examined. Surprisingly, because we observed a large overlap of transcriptional shifts induced by resveratrol and CR in all organs examined, our findings also suggest that a large component of the transcriptional program induced by CR may be independent of CR-mediated alterations in plasma IGF-1, or insulin".

5. SIRT1 activation increases skeletal muscle precursor cell proliferation.
so you will be able to grow more muscle:
Sirt1 increases skeletal muscle precursor ce... [Eur J Cell Biol. 2009] - PubMed - NCBI
For the first time, Sirt1 has been shown to increase MPC proliferation. These findings could have clinical significance since MPC proliferation has important implications in regulating skeletal muscle growth, maintenance, and repair, and the aging-related loss of skeletal muscle mass.

 

[O.N.]

This study was done with mouse embryo cell cultures. Did you even bother to read the full paper? It's proof of concept and nothing more. Besides, the body will activate mTOR by hundreds of mechanisms, inhibiting one will have next to no effect (besides, insulin is a far more powerful hormone than rsv). Ibuprofen is a good real world example of this, it will inhibit mTOR somewhat but protein synthesis is still unaffected due to the myriad of other ways to activate mTOR

Although we have butted heads in the past thanks for your positive response to people who misread information. thanks Oni.

 

[Stiffy]

Although we have butted heads in the past thanks for your positive response to people who misread information. thanks Oni.

even though he called your product Dildos?

(everyone likes da Poni)

 

[O.N.]

even though he called your product Dildos?

(everyone likes da Poni)

come back after you have read all of these reviews and before and after blood work...... Res100 Reviews and Blood tests | Wicked Supplements

• Ask yourself why do people write these reviews?
• why do people go to the effort to complete before and after blood work?

They must be feeling or doing something in order to warrant their time to do them.

 

[lkt004]

The research backs up the claims, most people will simply argue because they can, using google in order to sound smart.

 

[Stiffy]

come back after you have read all of these reviews and before and after blood work...... Res100 Reviews and Blood tests | Wicked Supplements

• Ask yourself why do people write these reviews?
• why do people go to the effort to complete before and after blood work?

Must be feeling or doing something in order to warrant their time to do them.

I do have respect for your persistence and empathy for your endeavor considering the hammering you cop on this forum and the other but have you thought of becoming a politician O.N. Julia herself doesn't "focus like a laser", "cut through" or "move forward" like you when trying to deliver a message. (Clive Palmer needs members).
Just a thought.

 

[Stiffy]

The research backs up the claims, most people will simply argue because they can, using google in order to sound smart.

mate it comes down to whether Res100 increases Test enough to make a difference as a stand alone supplement. Plus the fact O.N. seems to be going against convention wisdom with regard to PCT as Oni mentions previously.

 

[O.N.]

mate it comes down to whether Res100 increases Test enough to make a difference as a stand alone supplement. Plus the fact O.N. seems to be going against convention wisdom with regard to PCT as Oni mentions previously.

Although you see 85 reviews on the website soon to be a few more when i get a chance to update it there is many many many more which don't write on forums, the ones that email us or call. As i have also said time and time again find me another product with even half the reviews and blood work we have.....you cannot and when you do stumble across studies such as fenugreek boosting testosterone by an average of 98.1% you will see this is company funded and results are what they want you to see.

We are beyond that independent reviews and blood work are much better than a company funded controlled and altered study, yes when it happens we will get a proper study we have been in talks with melbourne university however this seems to be slow moving, however they sports faculty have already expressed their own interest in being involved.

As said you have to ask questions like why is there this many reviews and blood work, we have literally had hundreds of highly successful PCT's with our supplements to the point where yes you do have people on forums saying hands down best PCT ever vs previous outdated methods.

People use to ride horses before they drove cars its about time bodybuilding advanced too.

 

[lkt004]

Those blood test results look like pretty significant increases, obviously it's not a replacement for anabolic steroids, but a 10% increase in test can really only be a good thing for an athlete, combined with the protective effects it does exactly what it states.

Sure, i don't think ON should be talking about PCT, because technically using anabolic steroids is illegal, but that's another matter altogether .

 

[El Testicle]

even though he called your product Dildos?

(everyone likes da Poni)

Haha... Res100 = Dildos

Have heard nothing but crap about this stuff... All from people who would actually know. Not just from published reports from suppliers etc..

 

[O.N.]

Haha... Res100 = Dildos

Have heard nothing but crap about this stuff... All from people who would actually know. Not just from published reports from suppliers etc..

Really you have heard nothing but crap about it from people who have never used it........

i'll repeat the last post incase you missed it:

Although you see 85 reviews on the website soon to be a few more when i get a chance to update it there is many many many more which don't write on forums, the ones that email us or call. As i have also said time and time again find me another product with even half the reviews and blood work we have.....you cannot and when you do stumble across studies such as fenugreek boosting testosterone by an average of 98.1% you will see this is company funded and results are what they want you to see.

We are beyond that independent reviews and blood work are much better than a company funded controlled and altered study, yes when it happens we will get a proper study we have been in talks with melbourne university however this seems to be slow moving, however they sports faculty have already expressed their own interest in being involved.

As said you have to ask questions like why is there this many reviews and blood work, we have literally had hundreds of highly successful PCT's with our supplements to the point where yes you do have people on forums saying hands down best PCT ever vs previous outdated methods.

People use to ride horses before they drove cars its about time bodybuilding advanced too.

 

[Stiffy]

Those blood test results look like pretty significant increases, obviously it's not a replacement for anabolic steroids, but a 10% increase in test can really only be a good thing for an athlete, combined with the protective effects it does exactly what it states.

Sure, i don't think ON should be talking about PCT, because technically using anabolic steroids is illegal, but that's another matter altogether .

didn't want to get into a slanging match with O.N. considering all the shit he does cop, but we have already addressed the concerns over the test results O.N. posted earlier in this thread. To that it seemed O.N. did not clear up the matter/concerns.

Secondly, you're argument trying to back O.N. out of the conventional wisdom debate of PCT doesn't hold water. You can discuss Steroids, drugs and sheep shagging in this forum if you please. Part of O.N.'s business is doing this.

 

[El Testicle]

Really you have heard nothing but crap about it from people who have never used it........

i'll repeat the last post incase you missed it:

Although you see 85 reviews on the website soon to be a few more when i get a chance to update it there is many many many more which don't write on forums, the ones that email us or call. As i have also said time and time again find me another product with even half the reviews and blood work we have.....you cannot and when you do stumble across studies such as fenugreek boosting testosterone by an average of 98.1% you will see this is company funded and results are what they want you to see.

We are beyond that independent reviews and blood work are much better than a company funded controlled and altered study, yes when it happens we will get a proper study we have been in talks with melbourne university however this seems to be slow moving, however they sports faculty have already expressed their own interest in being involved.

As said you have to ask questions like why is there this many reviews and blood work, we have literally had hundreds of highly successful PCT's with our supplements to the point where yes you do have people on forums saying hands down best PCT ever vs previous outdated methods.

People use to ride horses before they drove cars its about time bodybuilding advanced too.

Zzzzz ....

 

[El Testicle]

didn't want to get into a slanging match with O.N. considering all the shit he does cop, but we have already addressed the concerns over the test results O.N. posted earlier in this thread. To that it seemed O.N. did not clear up the matter/concerns.

Secondly, you're argument trying to back O.N. out of the conventional wisdom debate of PCT doesn't hold water. You can discuss Steroids, drugs and sheep shagging in this forum if you please. Part of O.N.'s business is doing this.

Always down for some good 'ol fashioned sheep-shagging

Yeah... Kiwi's represent

 

[sjay]

Just noticed that it contains passiflora extract. Both passiflora and res are MAO inhibitors. Could there be a danger when used with other meds or stimulants like yohimbine?

Is reserveserateretol simlar to SERMS or AI's in its effect on e2? Is there a possibilty of estrogen rebound upon cessation? Not much data out there.

 

[El Testicle]

Just noticed that it contains passiflora extract. Both passiflora and res are MAO inhibitors. Could there be a danger when used with other meds or stimulants like yohimbine?

Is reserveserateretol simlar to SERMS or AI's in its effect on e2? Is there a possibilty of estrogen rebound upon cessation? Not much data out there.

Check out the brain on Sjay! ..

 

[Stiffy]

Res100 acts as an AI.

 

[sjay]

Res100 acts as an AI.

If its anything like arimidex then rebound could be an issue. Will do some mad googling when i get on the train.

 

[Stiffy]

If its anything like arimidex then rebound could be an issue. Will do some mad googling when i get on the train.

wait for O.N. or Oni to come back in. You'll hear from O.N. that's for sure.