That is all very well. Please forgive me if I am coming across like I am having a go at you as I am not. I have done some research on the main ingredient and have found it is used primarily as an anti-aging drug and may have some beneficial use for cancer sufferers. Other studies have found that it may be carcinogenic... One Korean study has found that it increases testosterone although it was very difficult to find verification of this study.
Some people swear by tribulus as a test booster based on some hazy findings in Bulgaria yet despite numerous trials on humans it has been found to have zero effect on increasing testosterone. It may increase LH in rats.
Forgive me if I sound cynical but you are pushing a product here.
references to studies can be found here:
http://wickedsupplements.com/products-page/hormone-support/res100/
here are some in reference to testosterone and sperm that i have found for you in relation to just resveratrol there are other studies on this page about the effects on testosterone of benzoflavone.
2. The Red Wine Polyphenol Resveratrol Displays Bilevel Inhibition on Aromatase in Breast Cancer Cells
Yun Wang, et al.
Toxicol. Sci., Jul 2006; 92: 71 – 77.
3. trans-Resveratrol, a Natural Antioxidant from Grapes, Increases Sperm Output in Healthy Rats M. Emília Juan, et al.
J. Nutr., Apr 2005; 135: 757 – 760
4. trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo.
S Shin, et al.
Arch Pharm Res, Jan 2008; 31(1): 83-7.
5. Inhibition of human estrogen synthetase (aromatase) by flavones
JT Kellis, Jr et al.
Science, Sep 1984; 225: 1032 – 1034.
some interesting studies on reveratrol:
Arch Pharm Res. 2008 Jan;31(1):83-7.Links
trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo.
Shin S, Jeon JH, Park D, Jang MJ, Choi JH, Choi BH, Joo SS, Nahm SS, Kim JC, Kim YB.
College of Veterinary Medicine, Chungbuk National University, Heungdeok-gu, Cheongju, Chungbuk 361-763, Korea.
“resveratrol did elicit an increase in blood testosterone concentration, testicular sperm counts and epididymal sperm motility by 51.6%, (smift notes: study in rabbits, Dosage 50mg/kg) 15.8% and 23.3%, respectively, without influence on sperm deformity. In conclusion, we propose that resveratrol has a positive effect on male reproductive function by triggering a penile erection, as well as enhancing blood testosterone levels, testicular sperm counts, and epididymal sperm motility.
========
trans-Resveratrol, a natural antioxidant from grapes, increases sperm output in healthy rats.
Juan ME, González-Pons E, Munuera T, Ballester J, Rodríguez-Gil JE, Planas JM.
Departament de Fisiologia, Facultat de Farmàcia, Universitat de Barcelona, E-08028 Barcelona, Spain.
“…Moreover, sperm counts were significantly greater in the resveratrol-treated rats (24.8 +/- 3.30 x 10(7)) than in the control group (14.1 +/- 0.80 x 10(7)), but sperm quality did not differ. Serum concentrations of gonadotrophins and testosterone were significantly higher in the resveratrol-treated group.
Dosage: 20 mg/(kg d) for 28 d
Testosterone, nmol/L
Control Group: 12.51 +/- 1.35
Treatment Group: 33.25 +/- 9.85
=======================
EFFECT OF RESVERATROL ON THE TESTOSTERONE PRODUCTION OF MOUSE PRIMARY LEYDIG CELL CULTURE
1Forgács, Zs, 2Somosy, Z, 2Telbisz, Á, 3Massányi, P, 3Lukác, N
1 National Institute of Chemical Safety, Budapest, Hungary
2 National “Frederic Joliot-Curie” Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary
3 Slovak University of Agriculture, Nitra, Slovak Republic
Resveratrol (Res) is a phytoestrogen and antioxydant of the red grape, which translocates and presents into the red wine. This compound is a known modulator of the balance of different sex hormones and founded to be an agonist of estrogen and androgen receptors. In our experiments primary cultures of mouse Leydig cells were exposed to resveratrol at the concentration range of 1.56 – 200 μM for 48 hours. Testosterone (T) content of the culture media was measured by enzyme linked immunosorbent assay (ELISA). The effect of Res on the T production was studied also in the presence of maximally stimulating amounts of human chorionic gonadotropin (1 IU/ml hCG) or dibutyryl cyclic adenosine monophosphate (1 mM db-cAMP). Res did not reduce the basal T production of Leydig cells up to 100 μM concentration. Moreover, interestingly Res stimulated the basal T production in the 12.5-50 μM concentration range. Whereas hCG (an LH receptor agonist) stimulated T production was decreased at 25 μM concentration of Res, while the db-cAMP (an effector of post-receptor signaling route) stimulated T response diminished even at 12.5 μM of Res. Res had also an additive effect on hCG stimulated T response at 3.12 μM concentration.
Our data suggest that Res may influence the testosterone production via direct or indirect modulation of LH-receptor mediated signals (at the receptor or secondary messenger cAMP level). Another possible mechanism of the effect of resveratol is a cross-talk effect between androgen and estrogen receptors.