How exactly does Resveratrol 100 increase Testosterone?
To understand how Resveratrol 100 increases Testosterone it’s important to understand the Hypothalamus-Pituitary-Testicular-Axis (HPTA).
In a normal healthy male, luteinizing hormone (LH) and follicle stimulating hormone (FSH) are sent from the brain (the pituitary) to stimulate the testes to make testosterone and sperm.
The release of LH & FSH from the pituitary is stimulated by Gonadotropin Releasing Hormone (GnRH) from the hypothalamus. The hypothalamus is stimulated to produce GnRH when it senses low levels of steroid hormones, such as testosterone and estrogen. (hypothalamus [GnRH] --- > pituitary [LH & FSH]--- > testes [testosterone])
On the other hand, when the brain detects high levels of steroid hormones it suppresses the release of GnRH, LH & FSH, and eventually testosterone production. This is called the negative feedback loop – the normal daily rhythm of hormone production.
Resveratrol 100 increases GnRH release by preventing the negative feedback of steroid hormones on the hypothalamus through GABAergic modulation and estrogen blockage*.
In other words, Resveratrol 100 offsets the suppression of steroid hormones in the brain, allowing the body to produce more testosterone than it normally would, by up-regulating GnRH and LH & FSH.