Jorn Trommelen on Facebook:
"A new study from our lab shows that eating large amounts of protein before sleep does not blunt muscle protein synthesis rates the next morning (either fasted MPS rates or the MPS response to protein). We speculated that there might be a negative feedback loop, where large amounts of protein might diminish the response to protein at subsequent meals. However, there was no difference between the groups.
These data suggest that every meal moment is a ''unique window of opportunity'' and that all meals work additively to optimize muscle protein synthesis rates in a day. If you miss a meal, you miss the opportunity to stimulate muscle protein synthesis. And it does not seem you can compensate that at subsequent meals. But as a protein meal can stimulate MPS for at least 5 hours, these data do not mean you should eat every 2-3 hours like it is 1990."
https://www.facebook.com/nutritiontactics/posts/1798394170375525
http://ajpendo.physiology.org/content/early/2016/10/25/ajpendo.00325.2016