I think all this is irrelevant if muscle or the reliance on muscle strength gained through training was to be one's mechanism of defense (in the situation you've alluded to in your post). I'd rather believe and trust in the ultimate performance drug of choice in such a situation, and that "drug" or hormone is non other than my endogenous adrenaline hormone. In my opinion, this hormone is the powerhouse of all other hormones, for without its presence in the right amount and at the right time, not even the most powerful anabolic steroid would do anything to help you move a weight let alone punch or kick someone in the head...if the situation (as protecting someone's own family) should call for it.
I also think, that strength athletes (who rely on pre-workout drinks/powders full of caffeine), or people who are heavily reliant on such an adrenal exhaustive drug such as caffeine, would fair less in a fight if compared with someone who does not rely on such a CNS stimulant to get themselves going.