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Does HGH Fragment 176-191 affect serum IGF-1 levels? Solid science please

evan

New member
Please back up your well researched opinion with some solid scientific research/links/papers etc


I have read 2 differing ideas and the labs dont seem to know anything about it. Lots of bro's say nah it doesnt but the monash article (i think) seems to indicate it does.


It shows AOD9604(oral 176-191) can affect IGF-1 levels in a dose dependant (1mg, 2mg) and accumulated timeline manner but I believe the article is presenting the oral administration method and not injections of this fragment. Presumably injections might be stronger? more potent?



2mg apparently ED can increaseIGF-1 by


40ng/ml - 110ng/ml(deviations) week 1
20ng/ml - 50ng/ml[1mg dose]


to


60ng/ml - 140ng/ml(deviations) week 12
30ng/ml - 80ng/ml[1mg dose]



that translates to similar figures in ug/L ie
40ug/L - 110ug/L week 1[2mg dose]
20ug/L - 50ug/L [1mg dose]
to
60ug/L - 140ug/L week12 [2mg dose]
30ug/L - 80ug/L [1mg dose]



if one were to extrapolate based on those results (if they are indeed accurate and true)

then at minimum a 500ug Oral dose ED would probably result in somewhere around the
10-25ug/L increase week 1 upto 15-40ug/L week12.


If so the question then is:
Is the injectable form more potent?
IF so how much more potent would it be? 2x?3x?6x?10x?


Hypothetically, if 500ug injection is about the same as 2000ug(2mg) oral then thats a considerable increase in serum IGF-1 levels!
Your levels in first couple of days could be elevated by 40-110ug/L and by week 12 60-140ug/L.



A friend, who admittedly did not have a baseline igf-1 measurement to start with (but had all the indicative hormones tested), had fasted serum levels tested and it measured out at approx 43nmol/l ie ~329ug/l. This was following 3days of ~400ug injection, twice a day ie 800ug total. Is on absolutely nothing else, nothing.
He did that baseline just to see if it changes with 100ug cjc+ 100ug ghrp2 ED injections(3 times a day).

Thats fairly high for his age group ~27 and he is not fit nor had been active/working out. He should have been more around the 200ish mark IMO......
 
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